Non-Invasive Intracranial Monitoring

Continuous insight into intracranial pressure, without entering the skull.

Centira is developing a bedside system that measures the brain's dynamic physiological response, continuously and non-invasively, bringing real monitoring to the at-risk patients who today are watched only in snapshots.

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The Silent Escalation Problem

Deterioration doesn't wait.
Today's monitoring does.

Elevated intracranial pressure and impaired brain compliance can trigger secondary injury, herniation, and death. Yet clinicians often can't see it coming in time. Intracranial monitoring today is binary: invasive precision for a few, episodic guesswork for everyone else.

Invasive ICP

Direct measurement, but requires neurosurgery, an ICU bed, and specialist staff, with infection and bleeding risk. Reserved for the sickest.

The Gap, where Centira lives

Patients at real risk, where invasive monitoring is unjustified, delayed, contraindicated, or removed too early. Detected late, after deterioration already shows.

Indirect Proxies

Neuro exams, CT, pupillometry, and transcranial Doppler are episodic, indirect, and operator-dependent, with no continuous, dynamic insight.

5.48M
Severe traumatic brain injury cases per year, globally. Most never receive invasive ICP monitoring.
12.2M
New strokes per year, globally. Hemorrhagic and ischemic patients sit in the gap for days.
<20%
Of at-risk neuro patients are monitored continuously today. The rest are watched on snapshots.
Let's Talk

Converting validated physics into the non-invasive standard for intracranial care.

For partnership, clinical collaboration, or investment conversations, we'd be glad to connect.

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